Set-shifting is the ability to move back and forth between tasks, operations, or mental sets in response to changing goals or environmental experiences. Set-shifting is a function primarily linked to the prefrontal cortex. Studies show difficulties in set-shifting are associated with anorexia nervosa, in particular to childhood perfectionism.  Researchers in London's King's College and Stanford University are currently looking at how set-shifting problems in anorexia patients may be addressed through Cognitive remediation therapy (CRT).

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